ICU Medical, Inc.
HomeICU Medical ProductsAbout ICU MedicalInvestors World Leader in Safety Medical Systems
Antimicrobial CLAVE® Connector

 

 

 

 

 

 

 

Product Information
Antimicrobial CLAVE Video
Technical Specifications
Product Literature
White Papers
Published Studies & Clinical Reports
Look to the Evidence!
Frequently Asked Questions
Contact Your Local Product Specialist
 

 

Antimicrobial CLAVE® NeedleFree Connector
 

 

Product Information

The Antimicrobial CLAVE is the first antimicrobial connector with dedicated internal fluid path technology. The same features that make the CLAVE the least likely to transmit bacteria over any other brand, now has the added feature of an antimicrobial additive.

CLAVE is the only connector which has been proven to reduce intraluminal catheter colonization in a randomized clinical trial. The reversed, split-septum technology and dedicated internal fluid path are the heart of what makes the CLAVE least likely to transmit bacteria than any other brand.

ICU Medical developed the Antimicrobial CLAVE to enhance the dedicated internal fluid path and further reduce the risk of bacterial ingress into the catheter. Ionic silver has been infused into all fluid path contact components which includes the internal cannula and split septum seal.

Antimicrobial CLAVE Efficacy Data

The Antimicrobial CLAVE provides at least a 4-log bacterial kill rate for a continuous 96-hour use life. This method of manufacturing eliminates the risk of the antimicrobial additive scraping or wearing away over time and repeated use.

  • Significant reduction in bacterial counts for a continued 96-hour use life on the surface of the septum.
  • Greater than a 4-log kill and a 99.99% reduction rate for Gram positive and Gram negative strains.

The Antimicrobial MicroCLAVE was proven effective with four gram positive and two gram negative bacterial strains.

  • Staphylococcus aureus
  • Staphylococcus epidermidis
  • Methicillin resistant Staphylococcus aureus - MRSA
  • Enterococcus faecalis- VRE
  • Pseudomonas aeruginosa
  • Klebsiella pneumoniae

 

Technical Specifications

Flowrate:
Deadspace:
Backpressure:
Functional Activations:
Other Features:

185mL / min.
0.06mL
75psig+
600
Latex Free

 

 

Product Literature
CLAVE Literature: CLAVE White Papers:
Antimicrobial CLAVE Brochure Antimicrobial CLAVE Efficacy Reports
  Compatibility with High Risk Infusates
  Evaluation of the CLAVE Technology and Resistance to Microbial Ingress, 2008
 
Published Papers & Clinical Reports for the CLAVE:
Moore C., et al: Significantly Decreased Rate of Catheter-Related Bloodstream Infections After Discontinuation of a Luer Access Device At an Academic Medical Center. From posters presented at the 2009 SHEA and 2010 APIC Annual Meetings and Facing the Challenge of CR-BSIs. Managing Infection Control; November, 2009
Ryder M., et al: Bacterial Transfer Through NeedleFree Connectors: Comparison of Nine Different Connectors. Presented at the Society for Healthcare Epidemiology of America Annual Scientific Meeting, April, 2007
Maragakis L., Bradley K., et al: Increased Catheter-Related Bloodstream Infection Rates After the Introduction of a New Mechanical Valve Intravenous Access Port. Infection Control and Hospital Epidemiology 2006, vol. 27, no. 1; 67-70
Bouza E., et al: A Needleless Closed System Device (CLAVE) Protects From Intravascular Catheter Tip and Hub Colonization: A Prospective Randomized Study. Journal of Hospital Infection 2003; 54: 279–287
Brown J.D., et al: The Potential for Catheter Microbial Contamination from a Needleless Connector. Journal of Hospital Infection 1997; 36:181-189
 
Get the Free Adobe® PDF Reader® to View Our Product Literature:

et Adobe Reader